Name | NNC45-0781 |
Synonyms | NNC45-0781 207277-66-5 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (3S,4R)- |
CAS | 207277-66-5 |
Molecular Formula | C27H29NO3 |
Molar Mass | 415.52 |
Density | 1.185±0.06 g/cm3(Predicted) |
Boling Point | 563.7±50.0 °C(Predicted) |
pKa | 9.87±0.60(Predicted) |
Storage Condition | -20℃ |
In vivo study | NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group. |